F14Y (p.Phe14Tyr) variant of ERBB3 (P21860)
F14Y (p.Phe14Tyr) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
F14Y (p.Phe14Tyr) variant details
- p.Phe14Tyr
- gnomAD 12-56080341-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.05
- MetaLR 0.24
- MetaSVM -0.50
- CADD 23.40
- PolyPhen-2 0.01
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available