F14L (p.Phe14Leu) variant of ERBB3 (P21860)
F14L (p.Phe14Leu) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
F14L (p.Phe14Leu) variant details
- p.Phe14Leu
- gnomAD 12-56080340-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.07
- MetaLR 0.12
- MetaSVM -0.95
- CADD 21.60
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available