E21G (p.Glu21Gly) variant of ERBB3 (P21860)
E21G (p.Glu21Gly) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
E21G (p.Glu21Gly) variant details
- p.Glu21Gly
- gnomAD 12-56080362-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.08
- MetaLR 0.23
- MetaSVM -0.68
- CADD 25.70
- PolyPhen-2 0.20
- SIFT 0.38
- Population evidence available
- Structural context available
- Literature evidence available