E21D (p.Glu21Asp) variant of ERBB3 (P21860)
E21D (p.Glu21Asp) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
E21D (p.Glu21Asp) variant details
- p.Glu21Asp
- gnomAD 12-56080363-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.06
- MetaLR 0.21
- MetaSVM -0.85
- CADD 19.70
- PolyPhen-2 0.03
- SIFT 0.58
- Population evidence available
- Structural context available
- Literature evidence available