D5N (p.Asp5Asn) variant of ERBB3 (P21860)
D5N (p.Asp5Asn) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
D5N (p.Asp5Asn) variant details
- p.Asp5Asn
- TOPMed rs1868337487
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.07
- MetaLR 0.20
- MetaSVM -0.90
- CADD 8.10
- PolyPhen-2 0.00
- SIFT 0.49
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available