D41E (p.Asp41Glu) variant of ERBB3 (P21860)
D41E (p.Asp41Glu) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
D41E (p.Asp41Glu) variant details
- p.Asp41Glu
- gnomAD 12-56083791-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.19
- MetaLR 0.31
- MetaSVM -0.59
- CADD 20.70
- PolyPhen-2 0.01
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available