A3G (p.Ala3Gly) variant of ERBB3 (P21860)
A3G (p.Ala3Gly) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A3G (p.Ala3Gly) variant details
- p.Ala3Gly
- TOPMed rs1868337458
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.05
- MetaLR 0.18
- MetaSVM -0.89
- CADD 17.40
- PolyPhen-2 0.00
- SIFT 0.50
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available