A27V (p.Ala27Val) variant of ERBB3 (P21860)
A27V (p.Ala27Val) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
A27V (p.Ala27Val) variant details
- p.Ala27Val
- gnomAD 12-56080380-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.07
- MetaLR 0.33
- MetaSVM -0.55
- CADD 33.00
- PolyPhen-2 0.00
- SIFT 0.97
- Population evidence available
- Structural context available
- Literature evidence available