A27T (p.Ala27Thr) variant of ERBB3 (P21860)
A27T (p.Ala27Thr) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
A27T (p.Ala27Thr) variant details
- p.Ala27Thr
- ExAC rs771442726
- gnomAD rs771442726
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.05
- MetaLR 0.30
- MetaSVM -0.63
- CADD 22.10
- PolyPhen-2 0.00
- SIFT 0.45
- Most common in the Latino/Admixed American population (allele frequency 2.4e-05)
- Structural context available