A27S (p.Ala27Ser) variant of ERBB3 (P21860)
A27S (p.Ala27Ser) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
A27S (p.Ala27Ser) variant details
- p.Ala27Ser
- gnomAD 12-56080379-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.04
- MetaLR 0.25
- MetaSVM -0.79
- CADD 21.30
- PolyPhen-2 0.00
- SIFT 0.60
- Population evidence available
- Structural context available
- Literature evidence available