A17S (p.Ala17Ser) variant of ERBB3 (P21860)
A17S (p.Ala17Ser) in ERBB3 (P21860) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
A17S (p.Ala17Ser) variant details
- p.Ala17Ser
- gnomAD 12-56080349-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.06
- MetaLR 0.18
- MetaSVM -0.89
- CADD 20.20
- PolyPhen-2 0.00
- SIFT 0.43
- Population evidence available
- Structural context available
- Literature evidence available