T27I (p.Thr27Ile) variant of ERBB2 (P04626)
T27I (p.Thr27Ile) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T27I (p.Thr27Ile) variant details
- p.Thr27Ile
- gnomAD rs1365546088
- Missense
- Variant Prioritization Score for Impact Estimate 0.442
- REVEL 0.23
- CADD 20.60
- PolyPhen-2 0.26
- SIFT 0.25
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available