R8S (p.Arg8Ser) variant of ERBB2 (P04626)
R8S (p.Arg8Ser) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
R8S (p.Arg8Ser) variant details
- p.Arg8Ser
- gnomAD rs2058006754
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.28
- CADD 13.20
- PolyPhen-2 0.03
- SIFT 0.44
- Population evidence available
- Structural context available