R8H (p.Arg8His) variant of ERBB2 (P04626)
R8H (p.Arg8His) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
R8H (p.Arg8His) variant details
- p.Arg8His
- Ensembl rs2145267929
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.22
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 9.7e-07)
- Structural context available