P18S (p.Pro18Ser) variant of ERBB2 (P04626)
P18S (p.Pro18Ser) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P18S (p.Pro18Ser) variant details
- p.Pro18Ser
- TOPMed rs1184958761
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.09
- CADD 17.80
- PolyPhen-2 0.00
- SIFT 0.43
- Population evidence available
- Structural context available