P17T (p.Pro17Thr) variant of ERBB2 (P04626)
P17T (p.Pro17Thr) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P17T (p.Pro17Thr) variant details
- p.Pro17Thr
- TOPMed rs1307888184
- gnomAD rs1307888184
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.07
- CADD 15.50
- PolyPhen-2 0.02
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available