P17S (p.Pro17Ser) variant of ERBB2 (P04626)
P17S (p.Pro17Ser) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P17S (p.Pro17Ser) variant details
- p.Pro17Ser
- cosmic curated COSV54074
- TOPMed rs1307888184
- gnomAD rs1307888184
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.18
- CADD 15.90
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available