P17L (p.Pro17Leu) variant of ERBB2 (P04626)
P17L (p.Pro17Leu) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
P17L (p.Pro17Leu) variant details
- p.Pro17Leu
- Ensembl rs2145269330
- Missense
- Variant Prioritization Score for Impact Estimate 0.301
- REVEL 0.15
- CADD 20.70
- PolyPhen-2 0.03
- SIFT 0.68
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available