L6W (p.Leu6Trp) variant of ERBB2 (P04626)
L6W (p.Leu6Trp) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
L6W (p.Leu6Trp) variant details
- p.Leu6Trp
- gnomAD 17-39700255-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.16
- CADD 21.00
- PolyPhen-2 0.00
- SIFT 0.30
- Population evidence available
- Structural context available
- Literature evidence available