L6S (p.Leu6Ser) variant of ERBB2 (P04626)
L6S (p.Leu6Ser) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
L6S (p.Leu6Ser) variant details
- p.Leu6Ser
- Ensembl rs2145267660
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.28
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.04
- Population evidence available
- Structural context available