L3P (p.Leu3Pro) variant of ERBB2 (P04626)
L3P (p.Leu3Pro) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
L3P (p.Leu3Pro) variant details
- p.Leu3Pro
- gnomAD 17-39700246-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.57
- CADD 28.50
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available