L16S (p.Leu16Ser) variant of ERBB2 (P04626)
L16S (p.Leu16Ser) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
L16S (p.Leu16Ser) variant details
- p.Leu16Ser
- Ensembl rs2145269169
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- REVEL 0.46
- CADD 24.50
- PolyPhen-2 0.97
- SIFT 0.06
- Population evidence available
- Structural context available