L16M (p.Leu16Met) variant of ERBB2 (P04626)
L16M (p.Leu16Met) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
L16M (p.Leu16Met) variant details
- p.Leu16Met
- gnomAD rs1225599701
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.32
- CADD 23.60
- PolyPhen-2 0.97
- SIFT 0.04
- Population evidence available
- Structural context available