L16L (p.Leu16Leu) variant of ERBB2 (P04626)
L16L (p.Leu16Leu) in ERBB2 (P04626) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
L16L (p.Leu16Leu) variant details
- p.Leu16Leu
- rs1225599701
- gnomAD 17-39700284-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.396
- CADD 13.20
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available