L15P (p.Leu15Pro) variant of ERBB2 (P04626)
L15P (p.Leu15Pro) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
L15P (p.Leu15Pro) variant details
- p.Leu15Pro
- TOPMed rs2058009009
- gnomAD rs2058009009
- Missense
- Variant Prioritization Score for Impact Estimate 0.571
- REVEL 0.63
- CADD 24.90
- PolyPhen-2 0.72
- SIFT 0.07
- Population evidence available
- Structural context available