L12P (p.Leu12Pro) variant of ERBB2 (P04626)
L12P (p.Leu12Pro) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
L12P (p.Leu12Pro) variant details
- p.Leu12Pro
- Ensembl rs2145268543
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- REVEL 0.64
- CADD 28.60
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available