G28D (p.Gly28Asp) variant of ERBB2 (P04626)
G28D (p.Gly28Asp) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data and structural context.
G28D (p.Gly28Asp) variant details
- p.Gly28Asp
- gnomAD rs1284110310
- Missense
- Variant Prioritization Score for Impact Estimate 0.871
- REVEL 0.93
- CADD 27.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available