G28A (p.Gly28Ala) variant of ERBB2 (P04626)
G28A (p.Gly28Ala) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
G28A (p.Gly28Ala) variant details
- p.Gly28Ala
- gnomAD rs1284110310
- Missense
- Variant Prioritization Score for Impact Estimate 0.863
- REVEL 0.92
- CADD 26.50
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available