G19R (p.Gly19Arg) variant of ERBB2 (P04626)
G19R (p.Gly19Arg) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
G19R (p.Gly19Arg) variant details
- p.Gly19Arg
- TOPMed rs1486972911
- gnomAD rs1486972911
- cosmic curated COSV54073
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.33
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.1e-05)
- Structural context available