G19A (p.Gly19Ala) variant of ERBB2 (P04626)
G19A (p.Gly19Ala) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G19A (p.Gly19Ala) variant details
- p.Gly19Ala
- TOPMed rs993479758
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.26
- CADD 19.60
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the African/African-American population (allele frequency 7.7e-05)
- Structural context available