G10W (p.Gly10Trp) variant of ERBB2 (P04626)
G10W (p.Gly10Trp) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
G10W (p.Gly10Trp) variant details
- p.Gly10Trp
- gnomAD 17-39700266-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.617
- REVEL 0.55
- CADD 24.60
- PolyPhen-2 1.00
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available