A4G (p.Ala4Gly) variant of ERBB2 (P04626)
A4G (p.Ala4Gly) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
A4G (p.Ala4Gly) variant details
- p.Ala4Gly
- TOPMed rs1428243929
- gnomAD rs1428243929
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.13
- CADD 24.30
- PolyPhen-2 0.04
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.7e-07)
- Structural context available