A21S (p.Ala21Ser) variant of ERBB2 (P04626)
A21S (p.Ala21Ser) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- cosmic curated COSV54071
- Ensembl rs2145269949
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.11
- CADD 13.90
- PolyPhen-2 0.05
- SIFT 0.58
- Population evidence available
- Structural context available