A14S (p.Ala14Ser) variant of ERBB2 (P04626)
A14S (p.Ala14Ser) in ERBB2 (P04626) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
A14S (p.Ala14Ser) variant details
- p.Ala14Ser
- gnomAD rs1442246817
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.23
- CADD 17.40
- PolyPhen-2 0.21
- SIFT 0.68
- Most common in the East Asian population (allele frequency 3.6e-05)
- Structural context available