Q39K (p.Gln39Lys) variant of EPHA3 (Ephrin type-A receptor 3)
Q39K (p.Gln39Lys) in EPHA3 (Ephrin type-A receptor 3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
Q39K (p.Gln39Lys) variant details
- p.Gln39Lys
- rs760801471
- NCI-TCGA Cosmic COSV6070
- ExAC rs760801471
- TOPMed rs760801471
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- REVEL 0.20
- CADD 23.90
- PolyPhen-2 0.93
- SIFT 0.34
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available