L16V (p.Leu16Val) variant of EPHA3 (Ephrin type-A receptor 3)
L16V (p.Leu16Val) in EPHA3 (Ephrin type-A receptor 3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L16V (p.Leu16Val) variant details
- p.Leu16Val
- NCI-TCGA Cosmic COSV1003
- cosmic curated COSV10034
- NCI-TCGA Cosmic COSV6072
- Ensembl rs1707007423
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.04
- CADD 13.40
- PolyPhen-2 0.01
- SIFT 0.14
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available