G3A (p.Gly3Ala) variant of EIF2AK4 (eIF-2-alpha kinase GCN2)
G3A (p.Gly3Ala) in EIF2AK4 (eIF-2-alpha kinase GCN2) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
G3A (p.Gly3Ala) variant details
- p.Gly3Ala
- gnomAD 15-39934201-TGGGG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.273
- CADD 27.20
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available