R4G (p.Arg4Gly) variant of EED (Polycomb protein EED)
R4G (p.Arg4Gly) in EED (Polycomb protein EED) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R4G (p.Arg4Gly) variant details
- p.Arg4Gly
- ExAC rs761126162
- gnomAD rs761126162
- Missense
- Variant Prioritization Score for Impact Estimate 0.455
- REVEL 0.34
- CADD 25.00
- PolyPhen-2 0.48
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available