K22R (p.Lys22Arg) variant of EED (Polycomb protein EED)
K22R (p.Lys22Arg) in EED (Polycomb protein EED) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
K22R (p.Lys22Arg) variant details
- p.Lys22Arg
- ExAC rs775661038
- TOPMed rs775661038
- gnomAD rs775661038
- Missense
- Variant Prioritization Score for Impact Estimate 0.481
- REVEL 0.38
- CADD 23.80
- PolyPhen-2 0.90
- SIFT 0.12
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available