K22N (p.Lys22Asn) variant of EED (Polycomb protein EED)
K22N (p.Lys22Asn) in EED (Polycomb protein EED) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
K22N (p.Lys22Asn) variant details
- p.Lys22Asn
- ExAC rs763154303
- TOPMed rs763154303
- gnomAD rs763154303
- Missense
- Variant Prioritization Score for Impact Estimate 0.434
- REVEL 0.39
- CADD 24.20
- PolyPhen-2 0.95
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available