G12V (p.Gly12Val) variant of EED (Polycomb protein EED)
G12V (p.Gly12Val) in EED (Polycomb protein EED) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
G12V (p.Gly12Val) variant details
- p.Gly12Val
- TOPMed rs907459561
- Missense
- Variant Prioritization Score for Impact Estimate 0.515
- REVEL 0.34
- CADD 26.90
- PolyPhen-2 0.13
- SIFT 0.03
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available