G12A (p.Gly12Ala) variant of EED (Polycomb protein EED)
G12A (p.Gly12Ala) in EED (Polycomb protein EED) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
G12A (p.Gly12Ala) variant details
- p.Gly12Ala
- TOPMed rs907459561
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.16
- CADD 22.80
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available