L66W (p.Leu66Trp) variant of EDNRB (Endothelin receptor type B)
L66W (p.Leu66Trp) in EDNRB (Endothelin receptor type B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
L66W (p.Leu66Trp) variant details
- p.Leu66Trp
- Ensembl rs2137639919
- Missense
- Variant Prioritization Score for Impact Estimate 0.714
- CADD 17.70
- PolyPhen-2 0.28
- SIFT 0.19
- Population evidence available
- Structural context available