E95Q (p.Glu95Gln) variant of EDNRB (Endothelin receptor type B)
E95Q (p.Glu95Gln) in EDNRB (Endothelin receptor type B) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes structural context.
E95Q (p.Glu95Gln) variant details
- p.Glu95Gln
- rs1282405488
- NCI-TCGA Cosmic COSV5752
- cosmic curated COSV57526
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- AlphaMissense 0.12
- MetaLR 0.10
- MetaSVM -1.03
- PolyPhen-2 0.15
- SIFT 0.06
- EVE 0.12
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available