R26W (p.Arg26Trp) variant of E2F1 (Transcription factor E2F1)
R26W (p.Arg26Trp) in E2F1 (Transcription factor E2F1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data.
R26W (p.Arg26Trp) variant details
- p.Arg26Trp
- TOPMed rs1386191320
- gnomAD rs1386191320
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.12
- CADD 21.40
- PolyPhen-2 0.25
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.5e-06)