R109W (p.Arg109Trp) variant of E2F1 (Transcription factor E2F1)
R109W (p.Arg109Trp) in E2F1 (Transcription factor E2F1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data.
R109W (p.Arg109Trp) variant details
- p.Arg109Trp
- ESP rs149803612
- ExAC rs149803612
- TOPMed rs149803612
- gnomAD rs149803612
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- REVEL 0.04
- CADD 23.90
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)