G84S (p.Gly84Ser) variant of E2F1 (Transcription factor E2F1)
G84S (p.Gly84Ser) in E2F1 (Transcription factor E2F1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data.
G84S (p.Gly84Ser) variant details
- p.Gly84Ser
- TOPMed rs1307523848
- gnomAD rs1307523848
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.05
- CADD 22.80
- PolyPhen-2 0.15
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)