S59Y (p.Ser59Tyr) variant of DYRK1A (Q13627)
S59Y (p.Ser59Tyr) in DYRK1A (Q13627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
S59Y (p.Ser59Tyr) variant details
- p.Ser59Tyr
- gnomAD 21-37472849-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.597
- MetaLR 0.14
- MetaSVM -0.90
- CADD 23.40
- PolyPhen-2 0.35
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available