S14Y (p.Ser14Tyr) variant of DYRK1A (Q13627)
S14Y (p.Ser14Tyr) in DYRK1A (Q13627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
S14Y (p.Ser14Tyr) variant details
- p.Ser14Tyr
- gnomAD 21-37472714-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.661
- MetaLR 0.39
- MetaSVM -0.35
- CADD 26.40
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available