Q61R (p.Gln61Arg) variant of DYRK1A (Q13627)
Q61R (p.Gln61Arg) in DYRK1A (Q13627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
Q61R (p.Gln61Arg) variant details
- p.Gln61Arg
- gnomAD 21-37472855-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- MetaLR 0.13
- MetaSVM -1.00
- CADD 19.80
- PolyPhen-2 0.44
- SIFT 0.16
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available